A Study Comparing the Effect of IV Labetalol and IV Lignocaine in Reducing the Rise in Blood Pressure and Heart Rate During Laryngoscopy and Intubation in Patients Undergoing Surgery at SMS Medical College Jaipur

A Randomised Study to compare intravenous Labetalol versus Lignocaine for Attenuation of Hemodynamic response to Laryngoscopy and Endotracheal intubation in ,SMS Medical college,Jaipur. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099712

Enrollment

Registered

2025-12-23

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Attenuating the pressor response to laryngoscopy and endotracheal intubation under general anaesthesia: Attenuating the pressor response to laryngoscopy and endotracheal intubation by u

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient undergoing elective surgical procedures under general anaesthesia and endotracheal intubation. 2.Patients willing to give written and Informed consent. 3. Adult patients aged 18 to 60 years. 4.Both sex. 5.Patients belonging to ASA (American society of Anesthesiologist ) grade I.

Exclusion criteria

Exclusion criteria: 1. History of chest pain/syncope/palpitations. 2. Any contraindications or history of hypersensitivity to study drugs. 3. Any respiratory problems. 4. Hepatic and renal issues. 5. Any abnormalities in the ECG. 6. Anticipated difficult intubation. 7. Patient should not be a part of any other study.

Design outcomes

Primary

Measure	Time frame
To determine the difference in changes in heart rate from baseline to different time intervals in two groups.Timepoint: 0,1,3,5,10 minutes after intubation.	—

Secondary

Measure	Time frame
To determine the difference in changes in hemodynamic responses (SBP,DBP,MAP)from baseline to different time intervals in two groups.Timepoint: 0,1,3,5,10 minutes after intubation.	—

Countries

India

Contacts

Public ContactDr Amrita Rani

SMS Medical college and Hospital Jaipur

Suncha87@yahoo.co.in9414077324

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026