Health Condition 1: D618- Other specified aplastic anemias and other bone marrow failure syndromes
Conditions
Interventions
Intervention1: Turmeric mouth wash: admitted pateints over a period of one year will be advised for turmeric mouth wash with 5ml of readymade solution of prescribed turmeric mouth wash 4 times a day a
Sponsors
Nisha kumari Khowal
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged equal to more than 6 years (children and adults) scheduled for autologous or allogeneic stem cell transplantation. Patients scheduled for myeloablative or reduced-intensity conditioning chemotherapy. For adults (more than 18 years Ability to provide written informed consent. For children (less than 18 years): Written informed consent from parent/guardian and assent from the child (age-appropriate). Capability to perform oral rinses independently or with caregiver assistance.
Exclusion criteria
Exclusion criteria: Known hypersensitivity to turmeric or curcumin. Presence of severe pre-existing oral lesions unrelated to chemotherapy (except mild gingivitis). Patients unwilling to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the effect of turmeric mouthwash on the incidence and grade of conditioning-induced oral mucositis in patients undergoing bone marrow transplantation.Timepoint: baseline and 1odays after intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the incidence of oral mucositis between patients receiving turmeric mouthwash with usual care and those receiving usual care alone. To compare the maximum severity grade of oral mucositis between the turmeric mouthwash group and the usual care group To assess and compare pain intensity associated with oral mucositis. To compare the duration of analgesic use for pain due to oral mucositis between the two groupsTimepoint: baseline and 1odays after intervention | — |
Countries
India
Contacts
Public ContactAnjali Rathee
AIIMS Delhi
Outcome results
None listed