Effect of exercise therapy and blood flow restriction therapy on muscle regeneration in patients with neuromotor injuries

MYOGENESIS STIMULATOR- Investigating The Difference In Molecular Mechanisms Of Improvement Following Regular Exercise Programme And Blood Flow Restriction Exercise For Patients With Neuromotor Injuries. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099705

Enrollment

Registered

2025-12-23

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G737- Myopathy in diseases classified elsewhere

Interventions

Intervention1: Myogenesis stimulator with blood flow restriction (BFR) assisted exercise therapy: Blood flow restriction will be applied using an inflatable pneumatic cuff placed over the intended mus

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with neuromotor injuries, Presence of muscle weakness or reduced muscle mass, Age-appropriate patients eligible for exercise rehabilitation, Willingness to participate and provide written informed consent (parental consent where applicable)

Exclusion criteria

Exclusion criteria: Unstable medical conditions contraindicating exercise therapy, Severe cardiovascular or peripheral vascular disease Local limb infection, open wounds, or contraindications to BFR, Patients unwilling or unable to comply with study procedures

Design outcomes

Primary

Measure	Time frame
Change in molecular markers of muscle regeneration (miR-27b and Myogenic Regulatory Factor-4)Timepoint: baseline, 4 weeks	—

Secondary

Measure	Time frame
Change in skeletal muscle mass (fat-free mass)Timepoint: Baseline and post-intervention of 3 weeks	—

Countries

India

Contacts

Public ContactDrLogaseni

Saveetha medical college hospital

drlaldv@gmail.com7299938038

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026