A study comparing two nerve based procedures for treating moderate to severe persistent allergic Rhinitis

Comparison of outcomes of posterior nasal neurectomy with radiofrequency ablation versus bipolar diathermy in patients with intractable moderate to severe persistent allergic rhinitis An Academic trial - NIL

Status

Recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099635

Enrollment

102

Registered

2025-12-22

Start date

Unknown

Completion date

Unknown

Last updated

2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: bipolar ablation of posterior nasal nerve: Bipolar ablation of the posterior nasal nerve is a minimally invasive procedure done to treat severe allergic rhinitis (persistent sneezing, r

Eligibility

Inclusion criteria

Inclusion criteria: 1. Persistent moderate to severe allergic rhinitis 2. 18-60 years males and females 3. No improvement in symptoms with 3 months usage of intranasal steroid spray

Exclusion criteria

Exclusion criteria: 1. Patients with gross deviated nasal septum 2. Patients with nasal polyps 3. Patients with acute rhinosinusitis 4. Patients with previous history of nose surgeries 5. Patients with previous history of radiation exposure to head and neck 6. Pregnant Women 7. Patients using oral contraceptive pills, antipsychotics 8. Patients with hypothyroidism

Design outcomes

Primary

Measure	Time frame
SNOT22 questionnaire (sinonasal outcome test)Timepoint: Preoperatively, 1 month, 3 months, 6 months	—

Secondary

Measure	Time frame
To compare duration of surgery, intraoperative bleeding between two groups To compare postoperative crusting using diagnostic nasal endoscopy between two groups To assess quality of life before & after the procedures between the two groups using RQLQ (Rhinoconjunctivitis quality of life questionnaire) To compare outcome of nasal symptoms after posterior nasal neurectomy between the two groups using VAS (visual analog scale) Timepoint: Preoperatively, 1 month, 3 months, 6 months	—

Measure

Time frame

To compare duration of surgery, intraoperative bleeding between two groups To compare postoperative crusting using diagnostic nasal endoscopy between two groups To assess quality of life before & after the procedures between the two groups using RQLQ (Rhinoconjunctivitis quality of life questionnaire) To compare outcome of nasal symptoms after posterior nasal neurectomy between the two groups using VAS (visual analog scale) Timepoint: Preoperatively, 1 month, 3 months, 6 months

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Countries

India

Contacts

Public ContactAakash Reddy Gade

All india institute of medical sciences, mangalagiri

ramesh.s@aiimsmangalagiri.edu.in9490713477

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 7, 2026