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Apache 2 vs Apache 4 study

Comparison of Apache II and Apache IV scores in predicting ICU mortality and clinical outcomes: A one-year prospective cohort study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/12/099606
Enrollment
1200
Registered
2025-12-22
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R652- Severe sepsis

Interventions

Intervention1: Nil: Nil Control Intervention1: Nil: Nil

Sponsors

PRAKRIYA HOSPITALS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Age more or equal to 18 years. 2. All ICU admissions during the study period. 3. Availability of clinical/physiological data within the first 24 hours of ICU admission to calculate APACHE II and APACHE IV.

Exclusion criteria

Exclusion criteria: 1. Admissions for palliative or comfort only care at entry (active DNAR with comfort only orders). 2. Refusal/withdrawal of consent (if consent model requires explicit consent). 3. Major data gaps rendering APACHE computation impossible despite prospective capture (e.g., more than 20 percent critical variables missing). 4. Extreme outliers (e.g., ICU stay more than 60 days) for sensitivity analyses; primary analysis will retain all unless clearly erroneous.

Design outcomes

Primary

MeasureTime frame
ICU mortalityTimepoint: 1 year—

Secondary

MeasureTime frame
length of ICU stay (days), duration of mechanical ventilation (hours), vasopressor use (yes/no, duration), renal replacement therapy (yes/no)Timepoint: 1 year—

Countries

India

Contacts

Public ContactDr Karthavya Sasuveghatta Lingappa

Prakriya hospitals

karthavyapractise@gmail.com919972800191

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026