Pain Control after Wisdom Tooth Surgery: Comparing Fentanyl Skin Patch and Diclofenac Tablets

Comparative evaluation of the efficacy of fentanyl transdermal patch and oral diclofenac sodium for pain management following mandibular third molar surgery: a split-mouth randomised controlled study. - NIL

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099589

Enrollment

Registered

2025-12-22

Start date

Unknown

Completion date

Unknown

Last updated

2026-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K011- Impacted teeth

Interventions

Intervention1: Fentanyl transdermal patch: Patients requiring bilateral third molar surgery will be given a single 50mcg fentanyl transdermal patch (will be instructed to remove after 72h) and placebo

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients requiring bilateral mandibular third molar surgery 2. Mandibular third molars with mild to moderate difficulty according to Pell and Gregory difficulty index 3. Patients with ASA I-II physical status

Exclusion criteria

Exclusion criteria: 1. Patients requiring bilateral mandibular third molar surgery 2. Mandibular third molars with mild to moderate difficulty according to Pell and Gregory difficulty index 3. Patients with ASA I-II physical status

Design outcomes

Primary

Measure	Time frame
VAS score for pain (1-10)Timepoint: Postoperatively at 1h, 12h, 24h and 72h	—

Secondary

Measure	Time frame
Post operative swelling will be assessed by a 5-line measurement using a standard flexible tape.Timepoint: preoperatively, then postoperatively at 24h and 72h;Maximum mouth openingTimepoint: preoperatively, then postoperatively at 24h and 72h	—

Countries

India

Contacts

Public ContactDr Chanchal Dharia

Terna Dental College and Hospital

sanjoshi99@gmail.com9869057337

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Jun 29, 2026