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A study on pain reduction after wisdom tooth surgery using two different local applications

comparative evaluation of efficacy of normal saline and 0.75 % of Ropivacaine HCL used as local applicat for pain control after impacted mandibular third molar surgery-RCT - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099539
Enrollment
26
Registered
2025-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Ropivacaine group 2: Patients in Group 2 (n=13) used 0.75% ordinary ropivacaine HCL to soak AGS in the extraction socket Control Intervention1: normal saline group 1: Patients in Group

Sponsors

DR MANJIRI JIVANRAO NAKADE
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Only non smoking with asa 1 status, normal bleeding and clotting time,normal prior use of analgesics, moderately impacted third molars with Pederson Index 3 to 5, all participants who signs informed consent

Exclusion criteria

Exclusion criteria: Patients were excluded if they declined participation, had systemic illness or immunocompromised status, allergy to anaesthetic agents, had an active infection (e.g., pericoronitis), or had any concomitant pathology (e.g., tumour, cyst), or were pregnant or nursing female participants.

Design outcomes

Primary

MeasureTime frame
To evaluate and compare the postoperative pain, patient s satisfaction towards postoperative pain control, postoperative supplemental analgesic rescue use (time) on using Normal Saline and Ropivacaine HCL soaked in Absorbable gelatin sponge when placed in the extraction socket after impacted mandibular third molar surgery.Timepoint: post-operatively at 5th hr, 12th hr,24th hr,48th hr,72th hr,96th hr,7th day

Secondary

MeasureTime frame
postoperative supplemental analgesic rescue use (time) on using Normal Saline & Ropivacaine HCL soaked in Absorbable gelatin sponge when placed in the extraction socket after impacted mandibular third molar surgery.Timepoint: post-operatively at 5th hr, 12th hr,24th hr,48th hr,72th hr,96th hr,7th day

Countries

India

Contacts

Public ContactDR MANJIRI JIVANRAO NAKADE

KLE V.K. Institute of Dental Sciences

viscollege@gmail.com8329795056

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026