Health Condition 1: D571- Sickle-cell disease without crisis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Adult patients (more than 18 years of age) 2.Subjects diagnosed with sickle cell anemia by hemoglobin high performance liquid chromatography (HPLC)
Exclusion criteria
Exclusion criteria: 1. History of chronic lung disease 2. Smokers 3. Patients with sickle cell trait and those with co-existing thalassemia or other hemoglobinopathies 3. Patients currently in vaso-occlusive crisis 4. Patients already receiving long-term continuous positive airway pressure therapy for any indication 5. Critically ill or hemodynamically unstable patients 6. Pregnant or lactating women
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Prevalence of sleep related breathing disorder in adults with sickle cell disease.Timepoint: At baseline (cross sectional study) | — |
Secondary
| Measure | Time frame |
|---|---|
| Association between sleep related breathing disorder & clinical severity of sickle cell disease.Timepoint: At baseline | — |
Countries
India
Contacts
All India Institute of Medical Sciences Nagpur