Health Condition 1: G20- Parkinsons disease
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Sponsors
Manipal College of Health Professions
Eligibility
Inclusion criteria
Inclusion criteria: Individuals diagnosed with PD and PSP under the criteria established by the MDS and NINDS-SPSP Age and gender-matched controls without symptoms of PD and PSP MRI reports showing no significant abnormality detected
Exclusion criteria
Exclusion criteria: Motor neuron disorders Multiple system Atrophy Secondary Parkinsonism; Drug induced Parkinsonism, Vascular Parkinsonism. Normal pressure hydrocephalus Patients diagnosed with Wilson s disease and sickle cell disease Cirrhosis of liver Patients with metal implants Previous intracranial bleed Head trauma Family history of PD Patients with prior neurological trauma, mass and tumour.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| QSM (ppb) and R2 (Hertz) values noted for Parkinsons and Progressive nuclear palsy.Timepoint: QSM (ppb) and R2 (Hertz) values will be noted at the end of each MRI scan. | — |
Secondary
| Measure | Time frame |
|---|---|
| Correlation of Clinical symptoms of the Parkinsons & Progressive Supranuclear PalsyTimepoint: At the end of each MRI scan | — |
Countries
India
Contacts
Public ContactDr Saikiran Pendem
Manipal Academy of Higher Education
Outcome results
None listed