Which Medicine Works Better for Post Gall Bladdar Surgery Pain Nalbuphine or Butorphanol in a Nerve Block

To evaluate the efficacy of nalbuphine versus butorphanol as adjuvants to 0.5 percent levobupivacaine in ultrasound-guided quadratus lumborum block for postoperative analgesia in laparoscopic cholecystectomy: a placebo controlled study - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099512

Enrollment

108

Registered

2025-12-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Quadratus Lumborum Block: After identifying the abdominal wall muscles as three layers with a linear probe (10-18 MHz, MyLab30

Esaote, Florence, Italy), the probe will be directed posteriorly to visualize the fascia transversalis (TF), thoracolumbar fascia, and QL muscles. Once the intervention area is disinfected, the local

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA physical status I and II. 2.Elective laparoscopic cholecystectomy.

Exclusion criteria

Exclusion criteria: 1.Carcinoma Gall bladder. 2.Hypersensitivity to study drugs. 3.Pregnant females. 4.Bleeding disorders. 5.Opioid addicts. 6.Patient refusal to participate in the study.

Design outcomes

Primary

Measure	Time frame
Post operative pain score with VAS and Time to rescue analgesia and total analgesic consumption.Timepoint: All patients will be asked to score their pain at 0, 1,2, 4, 6, 12, and 24 h after surgery.	—

Secondary

Measure	Time frame
Intraoperative monitoring Parameters(Noninvasive Blood pressure, Mean Arterial Pressure, Heart Rate, Respiratory Rate, Oxygen Saturation, ETCO2)Timepoint: Intraoperative monitoring will be done every 5 min till first 30 minutes, subsequently 10 min till 60 minutes and 15 minutes thereafter. ;Postoperative monitoring Parameters(Noninvasive Blood pressure, Heart Rate, Respiratory Rate, Oxygen Saturation, adverse effects)Timepoint: Monitored at 0, 1,2, 4, 6, 12, and 24 hours after surgery.	—

Measure

Time frame

Intraoperative monitoring Parameters(Noninvasive Blood pressure, Mean Arterial Pressure, Heart Rate, Respiratory Rate, Oxygen Saturation, ETCO2)Timepoint: Intraoperative monitoring will be done every 5 min till first 30 minutes, subsequently 10 min till 60 minutes and 15 minutes thereafter. ;Postoperative monitoring Parameters(Noninvasive Blood pressure, Heart Rate, Respiratory Rate, Oxygen Saturation, adverse effects)Timepoint: Monitored at 0, 1,2, 4, 6, 12, and 24 hours after surgery.

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Countries

India

Contacts

Public ContactDr Arshia Kaur Dhillon

Sri Guru Ram Das Institute of Medical Sciences and Research

gitzgitz@gmail.com9872981079

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026