Comparing two medications that is propofol and thiopentone in modified electroconvulsive therapy in patients with psychiatric disorders to keep the patients comfortable during the procedure

A comparative study of propofol and thiopentone for modified electroconvulsive therapy - A randomized controlled study - nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099482

Enrollment

Registered

2025-12-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F01-F99- Mental, Behavioral and Neurodevelopmental disorders

Interventions

Intervention1: ADMINISTRATION OF DRUGS : PROPOFOL AND THIOPENTONE: TO STUDY EFFECTIVENESS OF THESE TWO GROUPS IN MODIFIED ECTS BY ADMINISTERING PROPOFOL AT 1 TO 2 MG/KG AS INDUCING AGENT IN ONE GROUP

Eligibility

Inclusion criteria

Inclusion criteria: ASA GRADE 1 AND GRADE 2 PATIENTS PATIENTS WITH SCHIZOPHRENIA BIPOLAR AND MAJOR DEPRESSIVE DISORDERS REQUIRING MODIFIED ELECTROCONVULSIVE THERAPY

Exclusion criteria

Exclusion criteria: ASA GRADE 3 AND 4 PATIENTS PATIENTS WITH HISTORY OF ALLERGIC REACTION TO THE STUDY DRUGS RECENT CEREBROVASCULAR ACCIDENTS CARDIOVASCULAR DISORDERS RECENT MYOCARDIAL INFARCTION

Design outcomes

Primary

Measure	Time frame
RECOVERY PERIOD AND DURATION OF CONVULSIONS WITH BOTH GROUPSTimepoint: POST INDUCTION AND POST EMERGENCE	—

Secondary

Measure	Time frame
TO STUDY EFFECT OF BOTH GROUP DRUGS ON HEART RATE , SYSTOLIC AND DIASTOLIC PRESSURETimepoint: BEFORE INDUCTION , AFTER INDUCTION , POST ECT AT 1MINUTE , 3 MINUTES AND 5 MINUTES	—

Countries

India

Contacts

Public ContactM G DHORIGOL

KAHER JAWAHARLAL NEHRU MEDICAL COLLEGE

mallappadhorigol@gmail.com9844778096

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026