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To study the effects of oral Melatonin on pre operative Anxiety, Sedation and Induction dose of Thiopentone Sodium

The effects of Oral Melatonin on pre operative Anxiety,Sedation and Induction dose of Thiopentone Sodium in a Tertiary Care Centre - A Randomised Placebo control study - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/12/099481
Enrollment
60
Registered
2025-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 3- Administration

Interventions

Intervention1: Oral Melatonin 3mg: Oral Melatonin 3mg is given 1 hour before taking for surgery with sips of water and vitals noted at each 15 minutes interval till induction Control Intervention1: Mu

Sponsors

Sapthagiri institute of medical sciences and research center
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) ASA 1 and 2 2) Patients undergoing elective surgeries under GA 3) Informed consent

Exclusion criteria

Exclusion criteria: 1) Patients with difficult airway as assessed during PAC 2) Patients who have psychiatric,Neurological,Neuromuscular or Cardiovascular diseases or impairment of renal or hepatic functions

Design outcomes

Primary

MeasureTime frame
To compare the effect of Oral Melatonin versus Placebo on induction dose of ThiopentoneTimepoint: To compare the effect of Oral Melatonin versus Placebo on induction dose of Thiopentone, vitals noted every 15minutes till induction—

Secondary

MeasureTime frame
To compare the effect of Oral Melatonin versus Placebo on pre operative Anxiety, Sedation in patients undergoing general anaesthesia using haemodynamic parameters, visual facial analogue score and Ramsay Sedation score respectivelyTimepoint: Haemodynamic parameters and Sedation score will be noted at the time of medication and after 15minutes till the loss of eyelash reflex—

Countries

India

Contacts

Public ContactDr Shreyavathi R

Sapthagiri institute of medical sciences and research center

Shreyamurthy8993@gmail.com9880588325

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026