Health Condition 1: G620- Drug-induced polyneuropathy
Conditions
Interventions
Intervention1: Nil: Nil
Intervention2: Nil: Nil
Intervention3: Nil: Nil
Sponsors
Sri Ramachandra Institute Of Higher Education Research
Eligibility
Inclusion criteria
Inclusion criteria: Male and female patients diagnosed with non-metastatic breast cancer. Patients undergoing chemotherapy and/or radiotherapy more than 3cycles.
Exclusion criteria
Exclusion criteria: Use of assistive devices or walking aids, indicating reduced mobility. Muscle power less than grade 2 (not able to move limb against gravity). Pre-existing peripheral neuropathy from causes other than chemotherapy (e.g., diabetes, toxicity, infection). Advanced musculoskeletal disorders such as severe osteoarthritis, rheumatoid arthritis, chronic low back pain, or fibromyalgia with marked functional limitation. Severe cognitive or psychiatric impairment that may interfere with reliable reporting or test completion. Other neurological disorders affecting gait or sensory function (e.g., stroke, Parkinson s, multiple sclerosis).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of chemotherapy-induced peripheral neuropathy symptoms assessed using a validated clinical scale (EORTC QLQ-CIPN20) in non-metastatic breast cancer patients after at least three cycles of chemotherapy.Timepoint: Baseline, After 3 Cycles of Chemotherapy. | — |
Secondary
| Measure | Time frame |
|---|---|
| Peripheral neuropathy severity assessed using Revised Total Neuropathy Score (RTNS),Physical function assessed using Timed Up & Go (TUG) test, Vibration Perception threshold assessed using Biothesiometer.Timepoint: nil | — |
Countries
India
Contacts
Public ContactSurya S
Sri Ramachandra Institute Of Higher Education Research
Outcome results
None listed