Do Different Root Canal Sealers Affect Pain Relief and Healing After Treatment?

Comparative analysis of post operative pain and healing of periapical lesion using different sealers after non surgical endodontic treatment. A randomized controlled trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099478

Enrollment

Registered

2025-12-19

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: MTA FILLAPEX: MTA Fillapex is an endodontic sealer, while MTA Reparative is indicated for the treatment of perforations, root resorption, apical plug and pulp capping. Intervention2: EN

Eligibility

Inclusion criteria

Inclusion criteria: 1. HEALTHY PATIENTS BETWEEN 18-60 YEARS 2. PAI SCORE 2 OR MORE

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
This randomised control clinical study is designed to analyse and compare the mentioned sealers in terms of their role in post-operative pain and peri-apical healing potential.To check in reduction of Post-operative pain intensityTimepoint: 3 months, 6 months	—

Secondary

Measure	Time frame
Radiographic healing of periapical lesionTimepoint: 24 hours,48 hours & 7 days	—

Countries

India

Contacts

Public ContactDr Sadhana Raina

Government Dental College and Hospital,Nagpur

drsadhanaraina@gmail.com9423685967

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026