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A Clinical Study to Evaluate the Effect of Ozonized Water Used During Dental Scaling on Gum Health in Patients with Advanced Gum Disease

Effect of irrigation with ozonized water during ultrasonic scaling in the management of periodontitis: A randomized controlled clinical trial. - NIL

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099462
Enrollment
60
Registered
2025-12-19
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B968- Other specified bacterial agents as the cause of diseases classified elsewhere

Interventions

Intervention1: OZONIZED WATER: Route of administration-Subgingival irrigation Concentration - 2 ppm Duration- 20 seconds per tooth total duration 20 mins Control Intervention1: NORMAL SALINE: Route

Sponsors

ICMR STS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Stage III periodontitis (diagnosed according to 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions)31 Patients with minimum of 20 remaining teeth Subjects with PPD greater than or equal to 5mm in at least one site /quadrant. Subjects who had not received periodontal therapy within the last 6 months. Those who were willing to participate in the study

Exclusion criteria

Exclusion criteria: Patients with Stage III periodontitis (diagnosed according to 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions)31 Patients with minimum of 20 remaining teeth Subjects with PPD greater than or equal to 5mm in at least one site /quadrant. Subjects who had not received periodontal therapy within the last 6 months. Those who were willing to participate in the study

Design outcomes

Primary

MeasureTime frame
Results OF indices like Plaque Index (Turesky- Gilmore-Glickman modification of Quigley Hein), Gingival Index (Loe and Silness), Periodontal Pocket Depth (PD), Clinical attachment level (CAL), gingival recession and bleeding on probing (BOP).Timepoint: 1 MONTH

Secondary

MeasureTime frame
Results of biochemical analysis of salivaTimepoint: 1 month

Countries

India

Contacts

Public ContactDR NIRANJANA J MOHAN

Pms College of Dental Science and Research

ninjujm@gmail.com7907153733

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026