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Effect of Cold Saline Irrigation on Postoperative Pain After Pulpotomy in Permanent Molars

EFFECT OF CRYOTHERAPY ON POSTOPERATIVE PAIN DURING PULPOTOMY IN PERMANENT MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS - A RANDOMIZED CONTROLLED CLINICAL TRIAL - NIL

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099434
Enrollment
60
Registered
2025-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: R688- Other general symptoms and signs

Interventions

Intervention1: 2.5% sodium hypochlorite NaOCl at 2.5oC: Cotton pellets moistened with 2.5% NaOCl at 2.5oC will be used to achieve haemostasis for 5 minutes. After achieving haemostasis, the exposed pu

Sponsors

SGT Dental college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Permanent first and second maxillary and mandibular molars. 2. Moderate to severe Pain score on Heft-Parker Visual Analog Scale (HP -VAS). (No pain: 0 mm, Mild pain: more than 0 to less than 54 mm, Moderate pain: greater than 54 to less than 114 mm, Severe pain: more than 114 mm) 3. Teeth with positive response to cold test and Electric pulp test. 4. Teeth with negative response to palpation and percussion test. 5. Patients in good health, as determined by their medical history and responses to verbal questioning, will be included in this study. 6. Patients who have given informed consent will be included in the study

Exclusion criteria

Exclusion criteria: 1. Patients with periodontal probing depth greater than 4 mm. 2. Patients with swelling or sinus tract. 3. Tooth with periapical pathology on radiograph. 4. Teeth with no pulp exposure on caries excavation. 5. Patients with any medical condition- bleeding disorder, immunosuppressive condition or systemic diseases like hypertension or Diabetes Mellitus 6. Patients who took medications (Eg: analgesics) that could modify the pain assessment 12 hours before the first visit

Design outcomes

Primary

MeasureTime frame
To evaluate the effect of cryotherapy on postoperative pain for pulpotomy in permanent molars with symptomatic irreversible pulpitis.Timepoint: Assessment of Postoperative Pain using HP-VAS will be done at 6,12, 24 and 48 hours.

Secondary

MeasureTime frame
To compare the efficacy of 2.5% sodium hypochlorite at 2.5oC and at room temperature on postoperative pain for pulpotomy in permanent molars with symptomatic irreversible pulpitis.Timepoint: Assessment of Postoperative Pain using HP-VAS will be done at 6,12, 24 and 48 hours.

Countries

India

Contacts

Public ContactDr Ankita Sharma

Shree Guru Gobind Singh Tricentenary University

asankitasharma06@gmail.com09682575180

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026