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Comparing the effect of daily vs alternate day oral iron therapy for treatment of mild and moderate iron deficiency anemia in children

Daily vs alternate day oral iron therapy for treatment of mild and moderate iron deficiency anemia in children aged 5-18 years: A prospective open-labeled randomized controlled trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099431
Enrollment
200
Registered
2025-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E611- Iron deficiency

Interventions

Intervention1: Alternate day iron therapy: Receive an oral Iron syrup at a dose of 3mg/kg/day as a single morning dose on alternate day for 3 months Control Intervention1: Daily oral iron therapy: Rec

Sponsors

Dhanshree Vyas
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All Children aged 5 to 18 years having mild or moderate IDA as per WHO guidelines will be included in the study.

Exclusion criteria

Exclusion criteria: 1.Children having Hb less than 8g/dl i.e. severe anemia as per WHO guidelines 2.Children with anemia other than IDA 3.Children with chronic illness and congenital malformation 4.Patients who are not compliant to oral iron treatment after several reinforcement 5.Patients who are lost to follow up 6.Patients who received blood transfusions within past 3 months 7.Received multivitamin or iron supplement within 2 weeks before randomization.

Design outcomes

Primary

MeasureTime frame
hematological response after 3 months of oral iron therapy.Timepoint: hematological response after 3 months of oral iron therapy.

Secondary

MeasureTime frame
occurrence of adverse effects, change in hematological indices, change in iron profile parameters, and compliance to oral iron therapy.Timepoint: 3 months

Countries

India

Contacts

Public ContactDhanshree Vyas

Pramukhswami medical college, Karamsad

dhanshreevyas916@gmail.com09558170993

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026