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A study comparing two medicines- Clonidine and Tramadol, to see which one works better at stopping shivering after spinal anaesthesia

Comparative assessment of Clonidine and Tramadol on controlling post-spinal anaesthesia shivering. - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099389
Enrollment
128
Registered
2025-12-18
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N764- Abscess of vulva Health Condition 2: M959- Acquired deformity of musculoskeletal system, unspecified Health Condition 3: I839- Asymptomatic varicose veins of lower extremities Health Condition 4: N476- Balanoposthitis Health Condition 5: N401- Benign prostatic hyperplasia withlower urinary tract symptoms Health Condition 6: N400- Benign prostatic hyperplasia without lower urinary tract symptoms Health Condition 7: K400- Bilateral inguinal hernia, with obstruction, witho

Interventions

Intervention1: Tramadol 1 mg per kg body weight: Tramadol 1 mg per kg body weight given intravenously after the occurence of shivering post spinal anaesthesia Control Intervention1: Clonidine 1 mcg pe

Sponsors

MS Ramaiah Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA I and II patients posted for elective surgeries under spinal anaesthesia. Patients who develop shivering.

Exclusion criteria

Exclusion criteria: Refusal to consent for proposed study Infection at injection site History of any bleeding tendency, taking oral anticoagulants (INR more than 1.5) Uncontrolled comorbidities Allergy to the study drug Initial body temperature more than 38 degree celsius or less than 36 degree Celsius. Spine deformity Severe pulmonary or cardiac or hepatic or renal disease Contraindications to spinal anaesthesia Pre-existing neurological deficits

Design outcomes

Primary

MeasureTime frame
To assess the comparative efficacy of IV Clonidine versus IV Tramadol in controlling the shivering after spinal anaesthesiaTimepoint: 1,2,5,10,15 minutes post administering drug—

Secondary

MeasureTime frame
To assess the changes in hemodynamic parameters. To determine the incidence of post-operative shivering. To monitor the occurrence of any adverse effects (bradycardia, nausea, vomiting, dizziness, sedation, pruritus)Timepoint: 1,2,5,10,15,30 minutes post administering drug—

Countries

India

Contacts

Public ContactDr Navdeep

MS Ramaiah Medical College

nvdepkaur@gmail.com9945557290

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026