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A study to check the effect of injectable platelet rich fibrin on the speed of canine tooth movement during braces treatment.

Comparison of rate of maxillary canine retraction with and without submucosally administered injectable platelet-rich fibrin (i-prf) among orthodontic cases indicated for first premolar extraction a split mouth study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099332
Enrollment
24
Registered
2025-12-17
Start date
Unknown
Completion date
Unknown
Last updated
2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Injectable platelet rich fibrin: A 10 ml Blood sample will be taken from the patients forearm and collected in a non-silica-coated yellow cap tube of 10 ml. i-PRF is prepared by spinnin

Sponsors

Dr DHARINI M
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18-35 years, requiring extraction of first maxillary premolars for orthodontic treatment, Class 2 division 1, Bimaxillary protrusion cases

Exclusion criteria

Exclusion criteria: Patients with horizontal or vertical bone loss history of bone disorders, poor periodontal health, systemic diseases especially blood dyscrasias, pregnancy, and on steroid therapy, severe skeletal dysplasia in all three dimensions and with poor oral hygiene were excluded from the study.

Design outcomes

Primary

MeasureTime frame
1)To assess the rate of maxillary canine retraction in experimental site administered with i-PRF and control site(not administered with i-PRF) at different time intervals ( baseline T0- T6). 2) To compare the rate of maxillary canine retraction between experimental site administered with i-PRF and control site (not administered with i-PRF) at different time intervals ( baseline T0- T6).Timepoint: Evaluated at T0 baseline, 30 days (T1), at 60 days (T2),at 90 days (T3),at 120 days(T4),at 150 days (T 5) and at 180 days(T6 )—

Secondary

MeasureTime frame
To compare the rate of maxillary canine retraction within experimental site administered with i-PRF & within control site (not administered with i-PRF) at different time intervals ( baseline T0- T6).Timepoint: Evaluated at T0-T6 baseline (T0), at 30 days (T1), at 60 days (T2),at 90 days (T3),at 120 days(T4),at 150 days (T 5) & at 180 days(T6).;To compare the rate of maxillary canine retraction between male & females.Timepoint: Evaluated at T0-T2 baseline (T0), at 30 days (T1), at 60 days (T2).—

Countries

India

Contacts

Public ContactDHARINI M

Dayananda Sagar college of dental sciences, affiliated to Rajiv Gandhi University of Health Sciences

aravindm@dscds.edu.in9886111436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026