Comparative Evaluation of Calcium Hydroxide with Gingerol (Ginge-Cal), Calcium Hydroxide with Iodoform paste, Zinc Oxide Eugenol, and Endoflas as Obturating Materials in Pulpectomy of Primary Molars: A Randomized Clinical Study

Comparative Evaluation of Calcium Hydroxide with Gingerol (Ginge-Cal), Calcium Hydroxide with Iodoform paste, Zinc Oxide Eugenol, and Endoflas as Obturating Materials in Pulpectomy of Primary Molars: A Randomized Clinical Study - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099307

Enrollment

Registered

2025-12-17

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Calcium Hydroxide with Gingerol (Ginge-Cal): After obtaining informed consent, clinical and radiographic evaluations will be performed. Access opening and biomechanical preparation wi

Eligibility

Inclusion criteria

Inclusion criteria: Children of 4-8 years in good systemic health Tooth indicated for pulpectomy (Primary molars with irreversible pulpitis or necrotic pulp and at least two-thirds root length remaining Cooperative behavior (Frankl rating 3 or 4) Parents willing to provide consent for the study.

Exclusion criteria

Exclusion criteria: Medically compromised children Specially abled children Allergy to any of the components Severe root resorption or mobility

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study is to evaluate and compare the clinical and radiographic success rates of four obturating materials Ginge-Cal (Calcium Hydroxide + Gingerol), Calcium Hydroxide + Iodoform paste (Metapex), Zinc Oxide Eugenol, and Endoflas used in pulpectomy of primary molars, based on parameters such as pain, swelling, sinus tract, tenderness, mobility, and radiographic evidence of periapical/furcal healing, root resorption, or radiolucency assessed at follow-up intervals.Timepoint: Clinical and radiographic assessments at 1 week, 3 months, 6 months, and 12 months post- treatment.	—

Measure

Time frame

The primary outcome of the study is to evaluate and compare the clinical and radiographic success rates of four obturating materials Ginge-Cal (Calcium Hydroxide + Gingerol), Calcium Hydroxide + Iodoform paste (Metapex), Zinc Oxide Eugenol, and Endoflas used in pulpectomy of primary molars, based on parameters such as pain, swelling, sinus tract, tenderness, mobility, and radiographic evidence of periapical/furcal healing, root resorption, or radiolucency assessed at follow-up intervals.Timepoint: Clinical and radiographic assessments at 1 week, 3 months, 6 months, and 12 months post- treatment.

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactSharvari Ingle

SMBT Dental College and Hospital, Sangamner

vinayakumar53@gmail.com8830483436

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026