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A study comparing two injection treatments for knee osteoarthritis

Comparative evaluation of Intraarticular Dextrose Prolotherapy versus Triamcinolone injection in patients with Knee osteoarthritis - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099248
Enrollment
60
Registered
2025-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Comparative evaluation of Intraarticular Dextrose Prolotherapy versus Triamcinolone injection in patients with Knee osteoarthritis: Patients visiting the pain clinic undergo detailed hi

Sponsors

Pt. B. D. Sharma, PGIMS, Rohtak, Haryana
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with chronic knee osteoarthritis over 40 years of age, with radiographic evidence of Kellgren-Lawrence grade 2 or 3 osteoarthritis with no response to 3 months of conservative therapy.

Exclusion criteria

Exclusion criteria: Patients with Radiographic evidence of Kellgren-Lawrence grade IV osteoarthritis, History of recent knee surgery or arthroscopy within the last 6 months, Coagulopathy, History of any intraarticular injection over past 3 month, History of rheumatological disorder, Known allergy or hypersensitivity to dextrose, lidocaine, or corticosteroids, Diabetes mellitus

Design outcomes

Primary

MeasureTime frame
To evaluate and compare thr degree of pain relief achieved with intraarticular dextrose Prolotherapy v/s Triamcinolone injection using VAS scoreTimepoint: Evaluation of pain score using visual analogue scale(VAS) will be done -Before the procedure -After 2 weeks of intraarticular injection -After 1 month of intraarticular injection -After 3 months of intraarticular injection

Secondary

MeasureTime frame
To compare the two drugs in terms of - Disability index using WOMAC score (Western Ontario McMaster University Osteoarthritis Index) - Adverse events or complications at each follow-up if anyTimepoint: WOMAC Score will be recorded -Before the procedure -After 2 weeks of intraarticular injection -After 1 month of intraarticular injection -After 3 months of intraarticular injection

Countries

India

Contacts

Public ContactDr kethavath Pavan kumar

Pt. B. D. Sharma, PGIMS, Rohtak

Pardeepjakhar28@gmail.com8527072095

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026