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Finding the Most Comfortable and Effective Dental injection Method for Severe Tooth Pain.

COMPARATIVE EVALUATION OF THE PAIN AT SITE, ONSET OF ACTION AND ANESTHETIC EFFICACY OF CONVENTIONAL, PRECOOLED, PREHEATED AND BUFFERED LIDOCAINE IN PATIENTS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS: A RANDOMIZED DOUBLE BLINDED CLINICAL STUDY - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099244
Enrollment
40
Registered
2025-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: Z768- Persons encountering health services in other specified circumstances

Interventions

Intervention1: LOCAL ANASTHESIA [LIDOCAINE]: CONVENTIONAL, PRECOOLED, PREHEATED AND BUFFERED LIDOCAINE 1:80000 DILUTION OF ADRENALIN Control Intervention1: LOCAL ANESTHESIA: CONVENTIONAL, PRECOOLED,

Sponsors

B PRAGNYA
Lead Sponsor
AISHWARYA KARIGOUDAR
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients visiting the outpatient Department of Conservative Dentistry and Endodontics with deep carious lesions having moderate-to-severe pain (visual analog scale [VAS] more than 5) with SIP in the mandibular molar is included.

Exclusion criteria

Exclusion criteria: Hypersensitivity to lidocaine or sodium bicarbonate Patient with any systemic diseases Recent cardiac surgery Pregnancy or lactation Premedication Necrotic teeth with associated sinus tracts Advanced periodontitis Poor oral hygiene Presence of dental fractures Large periapical radiolucency (greater than 2 mm).

Design outcomes

Primary

MeasureTime frame
Primary outcome: Anesthetic efficacy of the inferior alveolar nerve block. Need for supplemental anesthesia.Success vs failure of pulpal anesthesia . Secondary outcomes: paint at site,onset of action and comparision Timepoint: Primary outcome: Anesthetic efficacy of the inferior alveolar nerve block. Need for supplemental anesthesia.Success vs failure of pulpal anesthesia .—

Secondary

MeasureTime frame
Secondary outcomes: paint at site,onset of action and comparision Timepoint: at the time of treatment—

Countries

India

Contacts

Public ContactB PRAGNYA

VYDEHI INSTITUTE OF DENTAL SCIENCES AND RESEARCH INSTITUTE

vids_principal@vimsmail.com9010444355

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026