This study checks how a special Ayurvedic enema therapy helps people with diarrhoea-type IBS and how it affects the good bacteria in the gut.

Effectiveness of Dwadashaprasutha Grahi Vasti in Yogavasti Schedule in Diarrhoea Predominant Irritable Bowel Syndrome and Gut Microbiota analysis in Sub Sample - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099231

Enrollment

Registered

2025-12-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K928- Other specified diseases of the digestive system

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Participants with IBS as per ROME4 criteria Participants fit for Niruhavasti and Anuvasana vasti Age group 20 to 50 years Willing to give consent

Exclusion criteria

Exclusion criteria: Diagnosed with Inflammatory bowel disease,colonic neoplasm,acute gastro intestinal condition Diagnosed case of systemic diseases like TB,HIV,Cardiac diseases and renal diseases Diagnosed case of uncontrolled Type2 diabetic mellitus,systemic hypertension,pregnant women and lactating mother Severe cases of IBS (IBS-Symptom severity scale score greater than 300)

Design outcomes

Primary

Measure	Time frame
1.The subject will be assessed using the IBS Symptom severity scale on 0th day,9th day,25th day 2.The stool examination using Real time PCR will be done on 0th day and 25th dayTimepoint: 0th day,9th day,25th day	—

Secondary

Measure	Time frame
1.To evaluate reduction in symptoms of grahani 2.Assessment of samyak niruha lakshana of dwadashaprasrutha grahi vasti as per samhitas on 3rd,5th and 7th dayTimepoint: 3rd day,5th day,7th day	—

Countries

India

Contacts

Public ContactDr Seena S

Government Ayurveda College and Hospital Tripunithura

seenas279@gmail.com9447190133

Outcome results