Health Condition 1: E101- Type 1 diabetes mellitus with ketoacidosis
Conditions
Interventions
Intervention1: Balanced crystalloids ( Ringers lactate): Ringers lactate as only fluid in DKA management both in resuscitation and maintenance fluid. For the duration of 12 months
Control Intervention
Sponsors
Tarun Rana
Eligibility
Inclusion criteria
Inclusion criteria: Adult patient more than or equal to 18 years of age has clinical criteria satisfying for DKA. blood glucose more than 200 Anion gap more than 10mmol per lit Bicarbonate level less than 18 Presence of beta hydroxy butyrate or ketone in blood or urine
Exclusion criteria
Exclusion criteria: Patient received treatment from outside facility in form of iv fluids more than 1 litre. Refered TO AIIMS for further care only. Had euglycemic DKA
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time of resolution of DKA from starting of treatment. Its based on lab criteria, pH7.35 bicarbonate 18 meq/litTimepoint: To find the time of DKA resolution, patient will be assessed every 2 hourly with venous blood gas. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare time to insulin pump discontinuation (hours) To compare electrolyte abnormalities including hyperkalemia, hypokalemia & hyperchloridemia. To compare intensive care unit admission & length of hospital stay. To compare total length of hospital stay. To compare in hospital all cause mortality To compare in hospital acute kidney injury. To compare major adverse kidney event within 30 daysTimepoint: With in 4 weeks | — |
Countries
India
Contacts
Public ContactDr Bharat Bhushan Bhardwaj
Aiims Rishikesh
Outcome results
None listed