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comparison of dexmedetomidine versus nalbuphine added to intrathecal 0.5 percent isobaric levobupivacaine for anaesthesia in lower limb orthopedic surgeries

Comparison of Effectiveness of Dexmedetomidine versus Nalbuphine as an Adjuvant with Intrathecal 0.5 Percent Isobaric Levobupivacaine in Lower Limb Orthopaedic Surgeries A Randomized Double - Blind Controlled trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099191
Enrollment
62
Registered
2025-12-16
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Intathecal Dexmedetomidine: 0.5% Isobaric Levobupivacaine(3ml)+Dexmedetomidine 5 g(0.05 ml drug from tuberculin syringe diluted in Distilled water (0.05ml) ) or Nalbuphine 1mg (0.1ml d

Sponsors

GMERS medical college and hospital, gotri
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA class I and II, BMI less than 35 kg per m2, elective orthopaedic below knee open surgeries.

Exclusion criteria

Exclusion criteria: patient refusal, coagulation, pregnancy, deformity of vertebral column, allergy to study drug, psychiatric or neurologic illnesses.

Design outcomes

Primary

MeasureTime frame
onset of sensory and motor blockTimepoint: onset of sensory and motor block from time of intrathecal drug injection—

Secondary

MeasureTime frame
duration of sensory & motor blockTimepoint: from intrathecal injection to regression of sensory block to s1 dermatome & recovery of motor function(bromage score 0)—

Countries

India

Contacts

Public ContactDr Bhavesh Dalwadi

GMERS Medical College and Hospital, Gotri, Vadodara

bhaveshkdalwadi@gmail.com9825042148

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026