Comparing outcome between Onlay and Sublay mesh repair in treatment of ventral hernias

A randomized control trial to evaluate the effectiveness of onlay and sublay mesh repair in the treatment of ventral hernia. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099168

Enrollment

Registered

2025-12-16

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Onlay and sublay mesh placement: Comparing mesh placement in onlay and sublay using cynoacrylate glue Intervention2: Suture material and cyanoacrylate glue: Onlay and sublay mesh repair

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients aged 18 to 75 years diagnosed with primary or incisional ventral hernia. 2.Fit for elective surgical repair using mesh. 3.Consent to participate in the study.

Exclusion criteria

Exclusion criteria: 1.Recurrent hernias. 2.Immunocompromised patients or on steroids. 3. Emergency hernia surgeries. 4.Known hypersensitivity to cyanoacrylate.

Design outcomes

Primary

Measure	Time frame
To compare the duration of surgery and early postoperative complications like seroma, surgical site infections, flap necrosis and duration of hospital stay in sublay and onlay mesh repair in the treatment of ventral herniasTimepoint: Assessing post operative seroma formation,flap necrosis on 6hrs,1 day,3rd and 7th day.	—

Secondary

Measure	Time frame
To compare the duration of surgery & early postoperative complications like seroma, surgical site infections, flap necrosis & duration of hospital stay in sublay & onlay mesh repair in the treatment of ventral hernia. Need for postoperative interventions, such as aspiration of seroma or wound resuturing, within the first 7 postoperative days.early wound-related morbidity, including wound edema or hematoma, assessed during the early postoperative period.Timepoint: Time-specific assessment of postoperative seroma formation at 6 hours, postoperative day 1 day 3 & day 7. Time-specific assessment of flap necrosis at 6 hours, postoperative day 1 day 3 & day 7. Postoperative pain assessment, measured using the Visual Analogue Scale (VAS) at 24 hours, day 3, & day 7.	—

Measure

Time frame

To compare the duration of surgery & early postoperative complications like seroma, surgical site infections, flap necrosis & duration of hospital stay in sublay & onlay mesh repair in the treatment of ventral hernia. Need for postoperative interventions, such as aspiration of seroma or wound resuturing, within the first 7 postoperative days.early wound-related morbidity, including wound edema or hematoma, assessed during the early postoperative period.Timepoint: Time-specific assessment of postoperative seroma formation at 6 hours, postoperative day 1 day 3 & day 7. Time-specific assessment of flap necrosis at 6 hours, postoperative day 1 day 3 & day 7. Postoperative pain assessment, measured using the Visual Analogue Scale (VAS) at 24 hours, day 3, & day 7.

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Countries

India

Contacts

Public ContactU Kavitha

Aarupadai Veedu Medical College

ramachandrvudu.subramanian@avmc.edu.in8608702876

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026