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To treat patients with missed abortion medically by mifepristone and misoprostol without doing any surgical procedure

Mifepristone and misoprostol in the treatment of missed abortion in first trimester - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099095
Enrollment
50
Registered
2025-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O046- Delayed or excessive hemorrhage following (induced) termination of pregnancy

Interventions

Intervention1: Mifepristone 200mg Misoprostol 800 mcg: Confirmed missed abortion is treated with tab mifepristone 200 mg followed by tab misoprostol 800 mcg pv after 24 hr Intervention2: Nil: Nil Cont

Sponsors

Sweta singh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Women with upt positive and diagnosed with missed abortion on ultrasound and has uterine size less than 12 weeks and age greater than 18 years

Exclusion criteria

Exclusion criteria: Women with age <18 years,post cesarean section,hb <8 g/dl, ectopic pregnancy

Design outcomes

Primary

MeasureTime frame
1.Intervention of missed abortion with medical management by mifepristone and misoprostol lead to expulsion of gsac which are more acceptable by women 2.Its efficacy and safety can be analysed by expulsion of product of conception 3.side effect like severe cramps and pain abdomen and severe bleeding pv,vomiting,fever 4. Need of surgical intervention like check D&E in case of excessive bleedingTimepoint: 1.Intervention of missed abortion in first trimester (12 weeks)with medical management by mifepristone and misoprostol lead to expulsion of gsac which are more acceptable by women 2.Its efficacy and safety can be analysed by expulsion of product of conception 3.side effect like severe cramps and pain abdomen and severe bleeding pv,vomiting,fever 4. Need of surgical intervention like check D&E in case of excessive bleeding

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Snehamay chaudhuri

Midnapore Medical College and hospital

snehamaychaudhuri@gmail.com9830538366

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026