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study of endotracheal cuff inflation with 2% alkalinised lignocaine for preventing Post-Operative Sore Throat (POST) and reducing emergence phenomena after tracheal extubation in adult patients undergoing general anaesthesia

A comparative study of endotracheal cuff inflation with 2 percentage alkalinised lignocaine vs air for preventing Post-Operative Sore Throat (POST) and reducing emergence phenomena after tracheal extubation in adult patients undergoing general anaesthesia - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/12/099094
Enrollment
50
Registered
2025-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M16- Osteoarthritis of hip Health Condition 2: N30-N39- Other diseases of the urinary system Health Condition 3: K00-K95- Diseases of the digestive system Health Condition 4: H60-H95- Diseases of the ear and mastoid process

Interventions

Intervention1: Nil: Nil

Sponsors

Self myself
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All adult patients undergoing elective surgery under general anaesthesia requiring cuffed endotracheal tube ASA1 ASA2 ASA3

Exclusion criteria

Exclusion criteria: Pregnancy. Allergy to local anaesthetics Those who are not willing for study Terminally ill patients Paediatric population

Design outcomes

Primary

MeasureTime frame
HR,BP,MAP, Post op sore throat, post op nausea and vomitingTimepoint: 1.Heart rate, BP, MAP will be recorded prior to extubation, immediately following extubation, and after the patient is shifted to the postoperative ICU. 2.Just after extubation, patients will be assessed for the incidence of cough postoperatively using the Minogue Cough Score and reassessed again at 1 hr, 6 hr, and 12 hr post-extubation of trachea. Will be assessed for postoperative sore throat (POST) using a sore throat score at 1 hr, 6 hrs, and 12hr—

Secondary

MeasureTime frame
To compare the incidence of postoperative cough following inflation of the endotracheal tube cuff with 2% alkalinised lidocaine versus airTimepoint: 1st hour, 6th hour & 12th hour;To assess postoperative emergence by comparing hemodynamic changes, including heart rate, blood pressure, & mean arterial pressure, after extubation in patients whose endotracheal tube cuffs were inflated with 2% alkalinised lignocaine versus air.Timepoint: Prior to extubation, immediately after extubation & after shifted to postop ICU;To compare the incidence of postoperative nausea & vomiting between patients whose endotracheal tube cuffs are inflated with 2% alkalinised lignocaine & those inflated with airTimepoint: After 12 hours;To assess patient satisfaction 12 hours after surgery under general anaesthesia, comparing patients whose endotracheal tube cuffs were inflated with 2% alkalinised lignocaine versus air.Timepoint: after 12 hours—

Countries

India

Contacts

Public ContactDr Annet Susan Abraham

Sree Uthradom Thirunal Academy of Medical Sciences, Thiruvananthapuram

annetabraham92@gmail.com7907576437

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026