Health Condition 1: E118- Type 2 diabetes mellitus with unspecified complications
Conditions
Interventions
Intervention1: Millet group: Intervention group in addition to standard diet compostion and 30 percent calories restriction along with physical activities will have at least one meal composed of pearl
Sponsors
Council of Science and Technology UP
Eligibility
Inclusion criteria
Inclusion criteria: Age 18 to 60 years Diagnosed to have type 2 diabetes. Type 2 diabetes mellitus will be defined by glycosylated hemoglobin more than 6.5 percent or fasting plasma glucose more than 126 mg per dL or random blood glucose more than 200 mg per dL and diabetes not requiring any oral hypoglycemic agents or insulin for glycemic control
Exclusion criteria
Exclusion criteria: History of allergy to millets Secondary diabetes Type 1 Diabetes Gestational diabetes. Use of nutritional supplements Pregnant or lactating women Known severe chronic liver disease- patients with liver cirrhosis (hepatitis B virus, hepatitis C virus, autoimmune hepatitis, or alcohol related liver disease Pharmacological treatment with immunosuppressants Patients who were on anti obesity drugs corticosteroids, or anti psychotics Acute infections malignancy Any condition that hinders compliance to the intervention
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.Insulin resistance by HOMA IR at 12 weeks in two groups 2.Glycemic variability ( TIR) by continuous glucose monitoring over 14 days Timepoint: 1.Insulin resistance by HOMA IR at 12 weeks in two groups 2.Glycemic variability ( TIR) by continuous glucose monitoring over 14 days | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Markers of inflammation( HsCRP, Tnf Alpha, IL6)-Timepoint: at 12 weeks in two groups | — |
Countries
India
Contacts
Public ContactDR RITU KAROLI
Dr. Ram Manohar Lohia Institute of Medical Sciences, Lucknow
Outcome results
None listed