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Regenerative Potential of Phenytoin, Metformin and MTA

Comparative Evaluation of Phenytoin, Metformin and Mineral Trioxide Aggregate as a Direct Pulp Capping Agents Using Cone Beam Computed Tomography - A Randomised Controlled Clinical Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099058
Enrollment
30
Registered
2025-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: 8- Other Procedures

Interventions

Intervention1: Phenytoin gel: Phenytoin gel was prepared using dispersion method. 0.25% of phenytoin, 1.5% of mannitol, sucrose and preservative added stirred continuously at room temperature. 2% of c

Sponsors

Aswini N
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients between 18-45 years of either gender Patients with asymptomatic maxillary and mandibular premolars and molars with radiographic evidence of deep caries approximating the pulp chamber Absence of tenderness to percussion and positive response to cold and electric pulp testing with good oral hygiene and no systemic disease

Exclusion criteria

Exclusion criteria: Symptomatic teeth Evidence of periapical pathology Negative response to pulp vitality testing

Design outcomes

Primary

MeasureTime frame
Absence of tenderness to percussion and positive response to cold and electric pulp testing Timepoint: 3 and 6 months

Secondary

MeasureTime frame
Evidence of Dentin Bridge formationTimepoint: 3 and 6 months

Countries

India

Contacts

Public ContactDr M Kavitha

Tamil Nadu Government Dental College and Hospital, chennai

aswininalathati@gmail.com9094947757

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026