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STUDY EFFECT OF ZOLENDRONIC ACID VS DENOSUMAB ON BACK PAIN IN PATIENTS WITH OSTEOPOROSIS IN TERTIARY CARE CENTRE -RANDOMIZED CONTROLLED STUDY

STUDY EFFECT OF ZOLENDRONIC ACID VS DENOSUMAB ON BACK PAIN IN PATIENTS WITH OSTEOPOROSIS IN TERTIARY CARE CENTRE -RANDOMIZED CONTROLLED STUDY - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/099057
Enrollment
56
Registered
2025-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M818- Other osteoporosis without currentpathological fracture

Interventions

Intervention1: STUDY EFFECT OF ZOLENDRONIC ACID ON BACK PAIN, IN PATIENTS WITH OSTEOPOROSIS: INJ ZOLENDRONIC ACID Control Intervention1: STUDY EFFECT OF DENOSUMAB ON BACK PAIN, IN PATIENTS WITH OSTE

Sponsors

school of medical sciences and research Sharda university
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age MORE THAN AND EQUAL TO 50 years Patient of any gender diagnosed with osteoporosis (T-score LESS THAN -2.5 on DEXA) Chronic low back pain (MORE THAN 3 months) VAS MORE THAN 4 Pain not relieved by NSAIDs AND opiods and physiotherapy

Exclusion criteria

Exclusion criteria: Prior use of bisphosphonates or denosumab in the last 12 months History of malignancy and metabolic bone disease (other than osteoporosis) Patients with traumatic fractures of the spine Patients on long term glucocorticoid therapy Any other cause of lower back ache

Design outcomes

Primary

MeasureTime frame
To compare the reduction in low back pain intensity (measured using the Visual Analog Scale [VAS]) over a 6-month period between patients receiving zoledronic acid and those receiving denosumab.Timepoint: 0 , 3 AND 6 MONTHS—

Secondary

MeasureTime frame
nilTimepoint: nil—

Countries

India

Contacts

Public ContactDR RAJNI RANJAN

school of medical sciences and research sharda university

orthoranjan04@gmail.com9711778515

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026