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A study in patients with wounds to see whether vacuum-assisted (suction) dressing helps wounds heal faster and improves skin graft success compared to regular dressings.

To evaluate the efficacy of Vaccum assisted closure therapy as a pretreatment modality for split thickness skin grafts - -

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/12/099052
Enrollment
54
Registered
2025-12-15
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L80-L99- Other disorders of the skin and subcutaneous tissue

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil

Sponsors

Datta Meghe Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18-70 years with acute or chronic wounds suitable for STSG. Wounds with exposed granulation tissue and no exposed bone, tendon, or major vessels. Patients willing to adhere to VAC therapy for the required pretreatment period. Informed consent was obtained for participation in the study.

Exclusion criteria

Exclusion criteria: Patients with wounds involving significant necrosis or infection resistant to treatment. The presence of exceedingly exposed bone, tendons, or major blood is not amenable to grafting. Patients with underlying medical conditions impairing wound healing (e.g., uncontrolled diabetes, severe peripheral vascular disease). Individuals on immunosuppressive therapy or with malignancies involving the wound area. Pregnant or lactating women. Patients with contraindications to VAC therapy, such as active bleeding disorders or inability to tolerate negative pressure. All patients not consenting for study

Design outcomes

Primary

MeasureTime frame
Graft uptake percentage of the grafted area at postoperative 7-14, measured by standardized digital planimetry from calibrated wound photographs (unit:%)Timepoint: Postoperative day 7-14

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactShravani Jawadi

Datta Meghe Institute of Education and Research (JNMC, Wardha)

drvmrewale@gmail.com8007887196

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026