A study to see whether a steroid medicine inside the breathing tube reduces cough and sore throat after surgery.

Comparison of intracuff Dexamethasone vs Normal saline for attenuation of post-extubation laryngotracheal morbidity. - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/099047

Enrollment

Registered

2025-12-15

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: - Health Condition 2: O- Medical and Surgical Health Condition 3: O- Medical and Surgical Health Condition 4: J387- Other diseases of larynx

Interventions

Intervention1: Intracuff Instillation of inj. Dexamethasone: In laparoscopic surgery, intracuff Instillation of inj. Dexamethasone 0.2 mg/kg diluted in NS after intubation Control Intervention1: Intra

Eligibility

Inclusion criteria

Inclusion criteria: ASA I, II, III Mallampati I and II Supine or trendelenberg position Duration: 2 to 3 hours Elective laparoscopic surgeries under GA with cuffed ETT

Exclusion criteria

Exclusion criteria: Refusal to consent ASA IV V Mallampati III IV Preexisting hoarseness, URI Steroid use, COPD, Asthma Known allergy to study drugs

Design outcomes

Primary

Measure	Time frame
Compare severity of Post extubation cough , sore throat and horsenessTimepoint: 1min, 5min, 10min, 15min, 30min, 60min, 6hours, 12hours, 24hours.	—

Secondary

Measure	Time frame
Compare post operative hemodynamic parametersTimepoint: Post operative 24 hours	—

Countries

India

Contacts

Public ContactDr Rutviksinh D Jadeja

B.J. Medical College & Civil Hospital.

dhrumit09@yahoo.com9327021192

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026