The use of Clonidine along with lignocaine to improve recovery and reduce pain in women undergoing hysterectomy surgery

Effect of Clonidine as an Adjuvant to Intravenous Lignocaine on Quality of Recovery in Total Laparoscopic Hysterectomy: A Randomised Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098948

Enrollment

Registered

2025-12-11

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N858- Other specified noninflammatory disorders of uterus

Interventions

Intervention1: Clonidine infusion as an adjuvant to Lignocaine infusion on Quality of Recovery: Inj. clonidine 1 mcg/kg body weight intravenously (IV) in ringer lactate 500 ml as infusion 30 minutes b

Eligibility

Inclusion criteria

Inclusion criteria: 1.Undergoing elective total laparoscopic hysterectomies under general anaesthesia 2.Age between 40 and 65 years 3.ASA I, II, III

Exclusion criteria

Exclusion criteria: Patient refusal ASA class four Chronic use of opioids Severe hypotension defined as mean arterial pressure less than 60 mmHg Bradycardia defined as heart rate less than 40 beats per minute Patients taking clonidine methyldopa beta blockers or calcium channel blockers Known allergy to amide type local anaesthetics

Design outcomes

Primary

Measure	Time frame
Quality of Recovery using QoR-15 scoreTimepoint: Day before surgery and on Postoperative day 0	—

Secondary

Measure	Time frame
Postoperative pain scores (VAS)Timepoint: 0h,4h,8h,12h,16h,20h,24h;Postoperative Morphine requirementTimepoint: Cumulative morphine consumption at 24h	—

Countries

India

Contacts

Public ContactJyotsna M

SRM Medical College Hospital and Research Centre

drvenkat94@gmail.com9894581455

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026