Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: Patients will receive 2mg/kg of intravenous Sugammadex for reversal of Rocuronium induced neuromuscular blockade
Control Intervention1: Neostigmine: Patients will receive 0.
Sponsors
Guru Gobind Singh Medical College Hospital, Faridkot
Eligibility
Inclusion criteria
Inclusion criteria: Patients aged 18 to 65 years, of either gender, giving valid informed and written consent. Patients belonging to American Society of Anaesthesiology (ASA) grade I and II. Patients receiving rocuronium as the neuromuscular blocking agent during surgery.
Exclusion criteria
Exclusion criteria: Patients with known allergies to Sugammadex or neostigmine. Patients with neuromuscular disorders that may interfere with neuromuscular function assessment. Patients with severe hepatic or renal impairment. Patients who are pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the time to achieve a Train of four (TOF) ratio of 0.9 by Sugammadex versus Neostigmine in reversing Rocuronium induced neuromuscular blockade (in minutes)Timepoint: Time to achieve TOF ratio of 0.9 (in minutes) | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time with both reversal agentsTimepoint: Time to extubation(in minutes) | — |
Countries
India
Contacts
Public ContactDr Sarvjeet Kaur
Guru Gobind Singh Medical College Hospital, Faridkot
Outcome results
None listed