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A Comparative Study of Papacarie, V-Carie-Solve, and Conventional Methods for Caries Removal in Primary Molars

COMPARATIVE EVALUATION OF THE EFFICACY, TIME TAKEN AND PAIN PERCEPTION OF PAPACARIE, V-CARIE-SOLVE AND CONVENTIONAL HAND INSTRUMENTATION FOR CARIES REMOVAL IN PRIMARY MOLARS: A RANDOMIZED CONTROLLED TRIAL - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/098862
Enrollment
66
Registered
2025-12-11
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: Papacarie: Papacarie is a papain-based gel. Its main active component is papain (a proteolytic enzyme from papaya) combined with chloramine (an antiseptic/softening agent), a thickening

Sponsors

Dr. Neha Battulwar
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Children aged 4 9 years. 2. Broad cavitated occlusal lesion with dentinal involvement and occlusal access (ICDAS Score 5 or 6 and should be 3 x 4 mm in dimension). 3. Radiograph showing dentinal caries not involving pulp. 4. The consistency of carious lesions ranges from soft to medium hard. 5. Color ranges from light yellow to brown. 6. Patients exhibiting Frankl s Behaviour Rating Scale score of 3 and 4.

Exclusion criteria

Exclusion criteria: 1. Cases requiring restorative treatment that is not of the Class I variety. 2. Teeth with history of spontaneous or nocturnal pain 3. Extensively damaged teeth. 4. Radiograph showing caries involving pulp. 5. Medically or developmentally compromising conditions.

Design outcomes

Primary

MeasureTime frame
1.To evaluate the clinical efficacy,microbial efficacy, time taken and pain perception of Papacarie, V-Carie-Solve and Conventional Hand Instrumentation for caries removal in primary molars. Timepoint: At Baseline and immediately postop—

Secondary

MeasureTime frame
To compare the clinical & microbial efficacy, time taken & pain perception of Papacarie, V-Carie-Solve & Conventional Hand Instrumentation for caries removal in primary molars.Timepoint: 12 months—

Countries

India

Contacts

Public ContactDR MILIND WASNIK

Swargiya Dadasaheb Kalmegh Smruti Dental College and Hospital ,Nagpur

milind.wasnik@sdk-dentalcollge.edu.in9975050807

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026