Health Condition 1: C50- Malignant neoplasm of breast
Conditions
Interventions
Intervention1: Exercise: Aerobic exercise - home based walking exercise for 3 days per week
Resistance training exercise - 2 days per week
Stretching and breathing exercise for the rest of the days
Sponsors
Dr Rose Babu
Eligibility
Inclusion criteria
Inclusion criteria: Female patients who are diagnosed with breast cancer (Stage 1 to stage 3) and about to undergo neoadjuvant or adjuvant chemotherapy (cyclophosphamide-anthracycline regimen). Normal cardiovascular, hepatic and renal function. Patients who are willing to participate.
Exclusion criteria
Exclusion criteria: Patients with Eastern Cooperative Oncology Group (ECOG) performance status more than 1. Currently with any musculoskeletal disturbances, severe respiratory illness, autoimmune diseases. Patients who are pregnant. Who had undergone major surgeries within past 3 months Known case of any psychiatric disorders, intellectual disabilities. Under regular moderate to high intensity exercise (after calculation of physical activity level (PAL). Receiving chronic anti-inflammatory medications for other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Inflammatory markerTimepoint: 3 time points. Baseline - before chemotherapy, 6 weeks- after mid and 12 weeks - at the end of chemotherapy cycles | — |
Secondary
| Measure | Time frame |
|---|---|
| Body composition, Muscle strength, Quality of lifeTimepoint: Baseline, 6 weeks after mid & 12 weeks at the end of chemotherapy cycles;Chemotherapy toxicity, Relative dose intensityTimepoint: 3 weeks, 6 weeks, 9 weeks & 12 weeks after every cycle of chemotherapy | — |
Countries
India
Contacts
Public ContactDr Biju Bahuleyan
Jubilee Mission Medical College and Research Institute
Outcome results
None listed