Health Condition 1: R50-R69- General symptoms and signs
Conditions
Interventions
Intervention1: Conservative maintenance fluid (50%-60% of Holliday-Segar formula): Conservative maintenance fluid which is 50%-60% of Holliday- Segar formula is to be given per day till the study endp
Sponsors
Dr Shalu Gupta
Eligibility
Inclusion criteria
Inclusion criteria: Children aged 1 year to 18 years on invasive mechanical ventilation and hemodynamically stable
Exclusion criteria
Exclusion criteria: 1. Congenital Heart Disease 2. Diabetic Ketoacidosis 3. Acute Kidney Injury 4. Known Chronic Disorders like Chronic Lung Disease and Chronic Kidney Disease 5. Raised Intra Cranial Pressure 6. Known Inborn error of metabolism 7. Severe Acute Malnutrition
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Percentage of fluid overload (FO%) in standard versus conservative maintenance fluid strategy in mechanically ventilated children at the end of 7 days or extubation, whichever is earlierTimepoint: At the end of 7 days or extubation, whichever is earlier | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of children developing Fluid overload percentage more than 10%Timepoint: 7 days or extubation, whichever is earlier;Ventilator Free Days (VFDs)/ PICU Free Days (PFDs)Timepoint: 28 Days;Pediatric Logistic Organ Dysfunction (PELOD-2) scoreTimepoint: 7 days | — |
Countries
India
Contacts
Public ContactDr Aryan Rajiv Raj
Lady Hardinge Medical College
Outcome results
None listed