A split face study comparing Microneedling Radiofrequency versus Microneedling Radiofrequency combined with Topical Insulin in management of post acne atrophic scars

A split face Comparative Interventional study to evaluate efficacy of Microneedling Radiofrequency versus Microneedling Radiofrequency combined with Topical Insulin in management of post acne atrophic scars - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098662

Enrollment

Registered

2025-12-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L905- Scar conditions and fibrosis of skin

Interventions

Intervention1: Insulin: Microneedling radiofrequency with topical Insulin Control Intervention1: Microneedling radiofrequency: simple Microneedling radiofrequency

Eligibility

Inclusion criteria

Inclusion criteria: 1.Presence of atrophic acne scars on both sides of the face 2.Age between 18 and 45 years, 3.Absence of post-acne scar treatment in the previous three months

Exclusion criteria

Exclusion criteria: 1.Presence of active acne lesions. 2.Patients having keloid scarring or keloidal tendency. 3.History of bleeding disorder and anticoagulant therapy. 4.Oral steroid therapy. 5.Active localised skin infection like warts, herpes and bacterial infection. 6.Pregnancy and lactation 7.Uncontrolled blood glucose levels and history of diabetes mellitus 8.prior laser treatment for acne scars within the last 3 months, 9.allergy to insulin 10.Patients refusing to give consent for the study

Design outcomes

Primary

Measure	Time frame
Change in scar score and appearance after treatmentTimepoint: baseline (week 0), week 4, week 8, week 12	—

Secondary

Measure	Time frame
1. Patient satisfaction score by Visual Analogue scale 2.Statistical significance of improvement (microneedling radiofrequency with topical insulin vs microneedling radiofrequency) 3. side effects evaluationTimepoint: Baseline (week 0), week 4, week 8, week 12	—

Countries

India

Contacts

Public ContactDr Jaseeba Gurpreet Dhingra

KLE Academy of Higher Education and Research Deemed to be University, Belagavi

shivakumarkpatil@gmail.com9844512315

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026