Health Condition 1: E038- Other specified hypothyroidism
Conditions
Interventions
Intervention1: Individualized Homoeopathic medicine: Individualized Homoeopathic medicine will be prescribed in potency appropriate to each patient s clinical presentation.
The medicines will be admin
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: 1.Biochemically confirmed diagnosis of primary hypothyroidism with Elevated serum TSH with concurrently decreased levels of T4, in women presenting with menstrual dysfunction presenting as any of the following conditions like Amenorrhea, Oligomenorrhea, Menorrhagia, Metrorrhagia, or Epimenorrhea. 2.Females aged 18 to 45 years diagnosed with primary hypothyroidism, under stable thyroxine therapy for at least 3 months, presenting with documented menstrual irregularities. 3.Documented alterations in gonadotropin levels (FSH and or LH), measured between day 2 and day 5 of the menstrual cycle, based on standard laboratory reference ranges. 4.Willingness to participate, with voluntary written informed consent obtained prior to enrolment.
Exclusion criteria
Exclusion criteria: 1.Current or recent (within past 3 months) use of oral hormonal contraceptives or hormone replacement therapy. 2.Pregnant or breastfeeding women. 3.Known cases of psychiatric disorders, autoimmune diseases, or serious systemic illnesses (e.g. malignancies, end stage organ failure). 4.Substance abuse or dependency, including alcohol or recreational drugs. 5.Known cases of PCOS with hyperandrogenism, endometriosis, DUB, pelvic inflammatory disease, bleeding disorders, or structural uterine anomalies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.The effectiveness of individualized Homoeopathic treatment in hypothyroid women with menstrual irregularities will be assessed by comparing menstrual cycle parameters from baseline to end of treatment (6 months), measured using a structured Menstrual Cycle Charting Diary completed by participants. 2.Serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) levels will be measured at baseline, 3rd month, and 6th month to evaluate hormonal changes in response to treatment. Timepoint: Baseline ,3rd month, after 6 months | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Thyroid function parameters including thyroid stimulating hormone, triiodothyronine & thyroxine will be assessed at baseline, at three months & at six months to monitor thyroid status during the intervention. 2. Improvement in menstrual regularity & menstrual pattern will be analysed along with the normalization of hormonal & thyroid profiles at all three assessment points to determine the correlation between biochemical outcomes & symptomatic outcomes.Timepoint: Baseline ,3rd month, after 6 months | — |
Countries
India
Contacts
Public ContactProfessor Dr Gautam pal
National Institute of Homoeopathy
Outcome results
None listed