Effectiveness of exercise training with reduced blood circulation, on Knee muscle strength in individuals who have undergone knee ligament surgery-a comparative study by random allocation of patients.

Effect of Blood Flow Restriction Therapy on Quadriceps Muscle Strength in patients with Anterior Cruciate Ligament Reconstruction Double Blinded Placebo-Controlled Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098638

Enrollment

Registered

2025-12-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S835- Sprain of cruciate ligament of knee

Interventions

Intervention1: Blood Flow Restriction therapy + Conventional Therapy: Participants will receive Blood Flow Restriction Therapy with conventional physiotherapy for 2 weeks. A pneumatic occlusion cuff

Eligibility

Inclusion criteria

Inclusion criteria: 1. Immediate post -op ACL reconstructed patients 2. Age more than 18 to 40 years 3. Both gender

Exclusion criteria

Exclusion criteria: 1.Chronic Hypertension (more than 160/100mmHg) 2. Lower limb tumors, fractures and surgeries (previous knee surgery in the same limb) 3.Infections in the operated leg 4.Injury to another Knee ligament or multi-ligament injury 5.Personal or Family history of bleeding disorder, deep venous thrombosis, peripheral artery disease , cerebrovascular disease 6.Cardiac demand- type pacemaker 7. Persons with active anticoagulant use 8.Inability to tolerate Blood Flow restriction (BFR) cuff

Design outcomes

Primary

Measure	Time frame
Quadriceps muscle strengthusing Handheld dynamometer and modified Medical Research Council (mMRC) for manual muscle testTimepoint: Day 3 and Day 14	—

Secondary

Measure	Time frame
Pain using Visual analog scaleTimepoint: Day 3 and Day 14;Knee range of motion using Inertial measurement unit (IMU), goniometerTimepoint: Day 3 and day 14	—

Countries

India

Contacts

Public ContactAndrew Babu

Christian Medical college, Vellore

amisha.dalara.ahs24@cmcvellore.edu.in8074705903

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026