A study comparing two combination treatments for acne scars- subcision with microneedling and subcision with Injectable Platelet rich fibrin.

Comparative evaluation of Subcision followed by Microneedling versus Subcision followed by Injectable Platelet-Rich Fibrin in the management of Atrophic Acne Scars - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098631

Enrollment

Registered

2025-12-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: L905- Scar conditions and fibrosis of skin

Interventions

Intervention1: NIL: NIL Intervention2: Subcision and Microneedling for acne scars: Subcision technique: The face will be prepared and draped in sterile fashion. Local anaesthesia will be administered

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients above 18 years of age. 2. Patients who have given written consent before treatment is commenced. 3. Patients with atrophic acne scars (rolling, boxcar, or ice pick). 4. Patients who are willing to comply with treatment protocols and follow-up visits

Exclusion criteria

Exclusion criteria: 1. Patients with history of hypertrophic scars and keloid. 2. Patients with active acne lesions. 3. Patients with contraindications to Subcision, Microneedling, or iPRF (e.g., bleeding disorders, coagulation disorders, any active skin infections like herpes, etc.). 4. Patients with unrealistic expectations. 5. Seropositivity for HIV, Hepatitis B and Hepatitis C

Design outcomes

Primary

Measure	Time frame
To assess scar improvement using Echelle d Evaluation Clinique des Cicatrices d acne (ECCA) scoreTimepoint: At the end of study (After 2 years)	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactHeeral Vadera

Jawaharlal Nehru Medical College, Sawangi, Meghe, Wardha

drbhushan81@gmail.com7066887353

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026