Comparing three drugs Dexmedetomidine, Esmolol and Magnesium in Sinus Surgery with Controlled Low Blood Pressure

Comparison of dexmedetomidine, esmolol and magnesium sulfate for hypotensive anaesthesia in functional endoscopic sinus surgery - Nil

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098620

Enrollment

Registered

2025-12-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: General Anaesthesia: Induction of anesthesia is achieved with glycopyrrolate, administered as an anticholinergic premedication to reduce secretions and prevent bradycardia, followed by

Eligibility

Inclusion criteria

Inclusion criteria: 1.ASA I II 2.Elective FESS

Exclusion criteria

Exclusion criteria: 1.Bradycardia less than 50 bpm 2.Cardiac blocks 3.Renal/hepatic impairment 4.Drug allergy

Design outcomes

Primary

Measure	Time frame
Monitoring of intra operative MAPTimepoint: MAP and heart rate will be monitored at 5-minute intervals till the end of surgery. The time required to achieve the target MAP of 60 70 mmHg will be recorded, along with the duration for which the target MAP is successfully maintained using the study drug infusion.	—

Secondary

Measure	Time frame
Monitoring of Blood loss,Field visibility, Recovery time, Side effectsTimepoint: at every 5 min till the surgery ends	—

Countries

India

Contacts

Public ContactDr Prabhjot Singh

Sri Guru Ram Das Institute of Medical Sciences and Research

sgrdanaesthesia@gmail.com09815632909

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026