Comparison of Dexmedetomidine And Ketamine as additives in Caudal Anaesthesia for Children Undergoing Inguinal Hernia Surgery

A randomized comparative study to evaluate the effectiveness of dexmedetomidine versus ketamine as adjuvant to caudal block in children undergoing inguinal hernia repair under general anaesthesia at SMS Medical College and Hospitals Jaipur - Interventional

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/12/098600

Enrollment

Registered

2025-12-08

Start date

Unknown

Completion date

Unknown

Last updated

2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K409- Unilateral inguinal hernia, without obstruction or gangrene

Interventions

Intervention1: Ketamine group: Patients in this group will receive caudal injection of bupivacaine 0.25 percentage (1ml/kg) + injection Ketamine 0.5 mg/kg Control Intervention1: Dexmedetomidine group:

Eligibility

Inclusion criteria

Inclusion criteria: 1.Guardian willing to given written informed consent for participation in the study. 2.Paediatric patients aged between 2 and 6 years. 3.Scheduled for elective inguinal hernia repair surgery. 4.Classified as American Society of Anaesthesiologists physical status 1 and 2

Exclusion criteria

Exclusion criteria: 1. Guardian refusal to provide consent. 2.Presence of cardiac dysrhythmia. 3.Mental retardation. 4.known allergy to any of the study drugs.

Design outcomes

Primary

Measure	Time frame
To assess and compare duration of post operative analgesia between two groupsTimepoint: Till 24 hours after completion of surgery	—

Secondary

Measure	Time frame
1.To assess and compare number of times rescue analgesia required in 24 hours post operatively in both groups. 2.To assess and compare the degree of sedation in both groups for 24 hours. 3.To assess and compare occurrence of any side effects. 4. To assess and compare peri operative hemodynamic parameters.Timepoint:	—

Countries

India

Contacts

Public ContactDr Rama Chatterjee

SMS Medical College and Hospital

chatterjeerama30@gmail.com9828622026

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026