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Comparison of Intrathecal Fentanyl and Dexmedetomidine with Low Dose Levobupivacaine for Spinal Anaesthesia in Below Umbilical Surgeries

Effect of adding fentanyl vs dexmedetomidine in subarachnoid block characteristics with low dose isobaric levobupivacaine 0.5% in below umbilical surgeries A Randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/098565
Enrollment
80
Registered
2025-12-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Fentanyl: As soon as the patient enters the operation theatre after attaching the monitor Following strict aseptic protocols spinal anesthesia was administered by injecting the drug int

Sponsors

Self
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I or II Elective infraumbilical surgeries under spinal anesthesia Written informed consent obtained

Exclusion criteria

Exclusion criteria: Patient refusal Known allergy to study drugs Patients using alpha 2adrenergic receptors antagonists calcium channel blockers angiotensin converting enzyme inhibitor Local infection at the injection site Sepsis and Septic shock

Design outcomes

Primary

MeasureTime frame
To assess the effect of Dexmedetomidine and fentanyl in terms of 1 Hemodynamic parameters heart rate HR systolic blood pressure SBP diastolic blood pressure DBP mean arterial pressure MAP 2 Oxygen saturation SpO2Timepoint: During intraoperative period the Heart Rate Blood Pressure SpO2 Monitored Every 3 Minutes for 30 Minutes Then Every 5 Minutes for 1 hours than every 15 minutes for next hours Until Surgery Completed

Secondary

MeasureTime frame
Time from spinal injection to first request for rescue analgesia Adverse effects such as bradycardia low blood pressure nausea vomiting itching drowsiness and respiratory depression were observed and treated as needed Timepoint: Time from spinal injection to first request for rescue analgesia

Countries

India

Contacts

Public ContactDr Sarfraj Ahmad

Rohilkhand medical college and hospital

sarfaraz_ahm2000@yahoo.com9027347787

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026