Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Inj dexmedetomidine 1mcg/kg: Study participants will receive nebulisation with inj dexmedetomidine 1mcg/kg diluted to 5 ml with normal saline 15 mins before induction of general anaest
Sponsors
Regional Institute of Medical Sciences Imphal
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of age group 18 to 60 years. 2.Patients of American Society of Anaesthesiologists (ASA) physical grade I or II of both genders.
Exclusion criteria
Exclusion criteria: Patient with a history of sore throat or upper respiratory tract infection. Hemodynamically unstable patients. Emergency patients. Patients with a history of allergy to local anesthetics. Patients with a history of allergy to dexmedetomidine. Patients with a history of cardiac, liver or renal disorders. Patients with a difficult airway where the anticipated duration of laryngoscopy exceeded 15 seconds.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the effect of airway nebulization with ropivacaine (0.75%) versus dexmedetomidine on the hemodynamic response on laryngoscopy and intubation in patients undergoing surgery under general anaesthesia. Timepoint: Baseline (T0), after nebulisation (T1), before tracheal intubation (T2), immediately after tracheal intubation (T3), 2 min after tracheal intubation (T4), during tracheal extubation (T5). | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare the cough response at extubation. To compare any adverse effects like hypotension, hypertension, tachycardia, bradycardia. Timepoint: 30 min | — |
Countries
India
Contacts
Public ContactDr Gojendra Rajkumar
Regional institute of medical sciences, Imphal
Outcome results
None listed