Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Sugammadex: Patients in Group S will receive injection sugammadex 2mg/kg intravenously for reversal of neuromuscular blockade
Control Intervention1: Neostigmine: Patients in Group N wil
Sponsors
All India Institute of Medical Sciences, Rishikesh
Eligibility
Inclusion criteria
Inclusion criteria: 18 to 65 years of age of either sex requiring muscle paralysis for any surgical indication with no contraindication for extubation and surgical duration upto 3 hours.
Exclusion criteria
Exclusion criteria: Patients with haemodynamic instability Patients requiring post operative ventilator support Patients receiving neuromuscular blocking agents other than aminosteroid Patients with preexisting neurological or neuromuscular disorder Patients with impaired renal function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to tracheal extubationTimepoint: after administration of the reversal agent(time 0 mins) to the removal of endotracheal tube in minutes | — |
Secondary
| Measure | Time frame |
|---|---|
| Time taken for train of four ratio to become more than or equal to 0.9Timepoint: after administration of the reversal agent(time 0 minutes) to the time to achieve TOF ratio more than or equal to 0.9 in minutes;Time to eye openingTimepoint: after administration of the reversal agent(time 0 minutes) to the time to achieve eye opening in minutes;Time to tongue protrusion & arm liftTimepoint: after administration of the reversal agent(time 0 minutes) to the time taken for tongue protrusion & arm lift in minutes | — |
Countries
India
Contacts
Public ContactANIRBAN BRAHMA ADHIKARY
All India Institute of Medical Sciences, Rishikesh
Outcome results
None listed