Health Condition 1: C679- Malignant neoplasm of bladder, unspecified
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: History of smoking: more than or equal to 1 pack-year exposure Smoking cessation for at least a week Scheduled for elective transurethral resection of bladder tumour (TURBT) surgery under general anaesthesia surgically resectable Carcinoma of urinary bladder Mild, Moderate, Severe chronic obstructive pulmonary disease (COPD) classified as GOLD Stage I, II, III respectively.
Exclusion criteria
Exclusion criteria: Patient refusal or unwillingness to participate Very Severe COPD (GOLD Stage IV), home oxygen therapy requirement, or oxygen saturation less than 92 percentage on room air Uncontrolled cardiovascular conditions: recent MI (within 6 months), unstable angina, or decompensated heart failure Neuromuscular or orthopaedic limitations for yoga Severe cognitive impairment Major surgery in the past 3 months and Minor surgery within last 2 weeks Chronic or regular practitioners of yoga or pranayama
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the impact of preoperative yoga interventions as adjunctive therapies on perioperative pulmonary function, clinical outcomes, and psychological well-being in adult smokers undergoing TURBT surgery under general anaesthesia.Timepoint: time line mentioned: Forced Vital Capacity (FVC)Data collection : Day 0 (Pre-Yoga, Baseline) Day of Surgery (Post-Yoga, Pre-Surgery) Day 1 and Day 3 Post-Surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the impact of preoperative yoga and pranayama on Postoperative clinical outcomes, such as Requirement for supplemental oxygen for more than 4 hours, ICU admission for any respiratory complications, Incidence of postoperative pulmonary complications (PPCs), including pneumonia and respiratory failure in adult smokers undergoing TURBT surgery under general anaesthesia.Timepoint: Timepoints mentioned: Postoperative Respiratory Support Requirements Parameters and complications assessed: -Need for supplemental oxygen (Yes/No, duration in hours postoperatively) -ICU admission rate and duration (Yes/No, ICU stay in hours/days) -Incidence of post operative pulmonary complications such as pneumonia, atelectasis or respiratory failure Data Collection: Post-Surgery (Day 1 and Day 3) ;To compare patient reported psychological well-being using validated tools ie. Surgical Fear Questionnaire (SFQ) and the State-Trait Anxiety Inventory (STAI) from baseline to day of surgery after preoperative yoga and pranayama in adult smokers undergoing TURBT surgery under general anaesthesia.Timepoint: Timepoints mentioned : 1.Surgical Fear Questionnaire (SFQ) (Validated for preoperative fear assessment) 2.State-Trait Anxiety Inventory (STAI) (Validated for perioperative anxiety evaluation) Data Collection: Day 0 (Pre-Yoga, Baseline) Day of Surgery (Post-Yoga, Pre-Surgery) ;To assess the impact of perioperative yoga intervention in reduction of inflammation, evaluated by Neutrophil-to-Lymphocyte Ratio (NLR) as a biomarker of surgical stress and systemic inflammation from baseline to post surgery in adult smokers undergoing TURBT surgery under general anaesthesia.Timepoint: Timepoints mentioned : Inflammatory Response (NLR) Outcome Measure: Neutrophil-to-Lymphocyte Ratio (NLR) (Derived from CBC with differential count) Data Collection: Day 0 (Pre-Yoga, Baseline) Day of Surgery (Post-Yoga, Pre-Surgery) Post-Surgery ;To assess the impact of | — |
Countries
India
Contacts
All India Institute of Medical Sciences Rishikesh