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To assess the effect of Arq-i Ajeeb in patient with chronic rhinosinusitis.

An open-label, single arm clinical study to evaluate the efficacy of Arq-i Ajeeb as an inhalation therapy (Inkibab) for the management of chronic rhinosinusitis (Waram Tajawif Al-Anf Muzmin) - NIL

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/12/098511
Enrollment
30
Registered
2025-12-05
Start date
Unknown
Completion date
Unknown
Last updated
2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J324- Chronic pansinusitis Health Condition 2: J329- Chronic sinusitis, unspecified

Interventions

Intervention1: Arq i Ajeeb: Two to five drops of Arq i Ajeeb mixed with five hundred ml hot boiling water given as a Inhalational Therapy twice daily for five to ten minutes for six weeks Control Inte

Sponsors

State Unani Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Participants aged 18 years to 50 years of either sex. Diagnosed cases of mild to moderate or waram tajawif al anf muzmin. Presence of at least two of the four cardinal symptoms: facial pain or pressure, hyposmia or anosmia, nasal obstruction, or nasal discharge, persisting for a minimum of 12 consecutive weeks. Presence of any of the following symptoms such as rhinorrhea, nasal congestion, frontal headache, nasal itching, impaired sense of smell, or frequent sneezing, persisting for more than 12 weeks. Paranasal sinus x ray showing positive findings consistent with chronic rhinosinusitis, including mucosal thickening, sinus opacity, or both. Ability and willingness to provide written informed consent.

Exclusion criteria

Exclusion criteria: Patient with deviated nasal septum. Patients with local nasal or paranasal sinus pathology such as mucocele, cyst, antrochoanal polyp, or history of facial trauma. Patients with diabetes mellitus or any other illness requiring long term medical treatment. Pregnant or lactating women. Patients with known significant pulmonary, cardiovascular, hepatic, renal, or systemic dysfunction. Patients with prior history of nose or paranasal sinus surgery. Patients with documented history of trauma to the nose or sinus region. Patients diagnosed with pulmonary tuberculosis (pulmonary koch) or with history of epistaxis. Patients with history of epistaxis. Patients unwilling or unable to attend regular treatment or follow up visits for the entire study duration. Any medical condition where the treating physician considers participation potentially harmful to the patient.

Design outcomes

Primary

MeasureTime frame
Disease specific Quality of life assessment by: Sino-nasal Outcome test (SNOT-22) Visual Analog ScaleTimepoint: At baseline and sixth week

Secondary

MeasureTime frame
Change in mucosal thickning and sinu opacity in radiological assessment. Change in Absolute eisinophil countTimepoint: At baseline and sixth week

Countries

India

Contacts

Public ContactDastgeer Ahmed

State Unani Medical College and Hospital

asifhussainusmani@gmail.com7905831926

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026