Health Condition 1: M844- Pathological fracture, not elsewhere classified
Conditions
Interventions
Intervention1: Fractionated intrathecal injection of 0.5% hyperbaric bupivacaine with fentanyl: A total of 3 ml intrathecal anaesthetic solution (2.5 ml of 0.5% hyperbaric bupivacaine + 0.5 ml fentany
Sponsors
Dr Mohanapriya S
Eligibility
Inclusion criteria
Inclusion criteria: 1 Age Above 65 Years 2 ASA Grade I,II,III 3 Patient Consent
Exclusion criteria
Exclusion criteria: 1 CONTRAINDICATION TO SPINAL ANAESTHESIA 2 CARDIOVASCULAR DISEASES( ISCHEMIC HEART DISEASE) 3 CEREBROVASCULAR DISEASE 4 SPINE TO DEFORMITIES 5 ALLERGY TO STUDY DRUGS
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of Hypotension MAP LESS THAN 65 mmHg OR MORE THAN OR EQUAL TO 20 PERCENTAGE fall from baseline Incidence of Bradycardia HR LESS THAN 60 bpm OR MORE THAN 20 PERCENTAGE fall from baselineTimepoint: Every 2 minutes for first 10 minutes,Then every 5minutes for next 2 hours and then every 15 minutes for next 4 hours upto 24 hours postoperatively Every 5 minutes for next 2 hours Every 15 minutes for next 4 hours Every 4 hours up to 24 hours postoperatively Every 2 minutes for first 10 minutes Every 5 minutes for next 2 hours Every 15 minutes for next 4 hours Every 4 hours up to 24 hours postoperatively | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 onset of sensory block time from completion of spinal injection T10 dermatomes 2 onset of motor block time from completion of spinal injection to achieving modified bromage score 3 3 two segment regression time time from maximum sensory level attained to regression by two dermatomes 4 maximum sensory level attained 5 total vasopressor requirement number of IV phenylphrine 20 microgram boluses required 6 block characteristics duration of sensory & motor block & total duration of anaesthesia 7 adverse events & complication nausea vomitting shivering giddinessTimepoint: 1 continuously assessed immediately after injection until T10 is reached upto end of surgery 2 continuously assessed until bromage 3 is reached intraoperatively 3 assessed periodically regression occurs 4 max sensory level attained every 10mins upto 24 hours 5 from onset of block until the end of surgery 6 intraoperative postoperative period upto 24 hours 7 intraoprative & up to 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactDr Venkatraman
SRM MEDICAL COLLEGE HOSPITAL AND RESEARCH CENTRE
Outcome results
None listed